Genomics and Proteomics MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Genomics and Proteomics, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Genomics and Proteomics MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of Genomics and Proteomics mcq questions that explore various aspects of Genomics and Proteomics problems. Each MCQ is crafted to challenge your understanding of Genomics and Proteomics principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our Genomics and Proteomics MCQs are your pathway to success in mastering this essential Bioinformatics topic.

Note: Each of the following question comes with multiple answer choices. Select the most appropriate option and test your understanding of Genomics and Proteomics. You can click on an option to test your knowledge before viewing the solution for a MCQ. Happy learning!

So, are you ready to put your Genomics and Proteomics knowledge to the test? Let's get started with our carefully curated MCQs!

Genomics and Proteomics MCQs | Page 3 of 12

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Q21.
The major challenges in genome assembly are sequence errors, contamination by bacterial vectors, and repetitive sequence regions.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q22.
When a sequence is generated from ____ ends of a single clone, the distance between the two opposing fragments of a clone is fixed to ________ meaning that they are always separated by a distance defined by a _____ length (normally 1,000 to 9,000 bases).

a.

both, an uncertain range, clone

b.

one, an uncertain range, clone

c.

both, a certain range, clone

d.

both, a certain range, gene

Discuss
Answer: (c).both, a certain range, clone
Q23.
Which of the following is untrue about base calling and assembly programs?

a.

The first step toward genome assembly includes derive base calls

b.

The first step toward genome assembly includes assigning associated quality scores

c.

One of the steps is to assemble the sequence reads into contiguous sequences

d.

There is no identifying overlap between sequence fragments

Discuss
Answer: (d).There is no identifying overlap between sequence fragments
Q24.
Which of the following is incorrect?

a.

Initial DNA sequencing reactions generate short sequence reads from DNA clones

b.

To assemble a whole genome sequence, these short fragments are joined to form larger fragments

c.

The average length of the reads is about 50 bases

d.

A number of overlapping contigs can be further merged to form scaffolds

Discuss
Answer: (c).The average length of the reads is about 50 bases
Q25.
Which of the following is incorrect about Phred?

a.

It is a UNIX program

b.

It doesn’t give a probability score in output

c.

It is used for base calling

d.

It uses a Fourier analysis to resolve fluorescence traces and predict actual peak locations of bases

Discuss
Answer: (b).It doesn’t give a probability score in output
Q26.
Which of the following is incorrect about Phrap?

a.

It aligns individual fragments in a pairwise fashion using the Smith–Waterman algorithm

b.

It doesn’t take input from Phred

c.

It is used for sequence assembly

d.

It is a UNIX program

Discuss
Answer: (b).It doesn’t take input from Phred
Q27.
VecScreen is a primarily aimed for sequence assembly.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (b).False
Q28.
Which of the following is incorrect about EULER?

a.

It is an assembly algorithm

b.

It uses a Eulerian Superpath approach, which is a polynomial algorithm

c.

In this approach, a sequence fragment is broken down to tuples of five nucleotides

d.

The tuples are distributed in a diagram with numerous nodes that are all interconnected

Discuss
Answer: (c).In this approach, a sequence fragment is broken down to tuples of five nucleotides
Q29.
TIGR Assembler is a UNIX program from TIGR for assembly of large shotgun sequence fragments.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q30.
Which of the following is incorrect about ARACHNE?

a.

It accepts base calls with associated quality scores assigned by Phred as input

b.

It is a free UNIX program

c.

It is for the assembly of whole-genome shotgun reads

d.

It doesn’t involve heuristic approach

Discuss
Answer: (d).It doesn’t involve heuristic approach
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