Genomics and Proteomics MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Genomics and Proteomics, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Genomics and Proteomics MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of Genomics and Proteomics mcq questions that explore various aspects of Genomics and Proteomics problems. Each MCQ is crafted to challenge your understanding of Genomics and Proteomics principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our Genomics and Proteomics MCQs are your pathway to success in mastering this essential Bioinformatics topic.

Note: Each of the following question comes with multiple answer choices. Select the most appropriate option and test your understanding of Genomics and Proteomics. You can click on an option to test your knowledge before viewing the solution for a MCQ. Happy learning!

So, are you ready to put your Genomics and Proteomics knowledge to the test? Let's get started with our carefully curated MCQs!

Genomics and Proteomics MCQs | Page 7 of 12

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Q61.
Which of the following is incorrect about a microarray?

a.

It is a slide attached with a high-density array of immobilized DNA oligomers representing the entire genome of the species under study

b.

Array of immobilized DNA oligomers cannot be cDNAs

c.

Each oligomer is spotted on the slide and serves as a probe for binding to a unique complementary cDNA

d.

It is the most commonly used global gene expression profiling method

Discuss
Answer: (b).Array of immobilized DNA oligomers cannot be cDNAs
Q62.
which of the following is incorrect about Oligonucleotide Design in A microarray?

a.

DNA microarrays are generated by fixing oligonucleotides onto a solid support

b.

The oligonucleotide array slide represents thousands of preselected genes from an organism

c.

The length of oligonucleotides is typically in the range of twenty-five to seventy bases long

d.

The oligonucleotides don’t react with cDNA samples

Discuss
Answer: (d).The oligonucleotides don’t react with cDNA samples
Q63.
Which of the following is incorrect about Data Collection?

a.

The two-color microarray uses multiple dyes at times

b.

The most common type of microarray protocol is the two-color microarray

c.

The cDNAs are obtained by extracting total RNA or mRNA from tissues or cells and incorporating fluorescent dyes in the DNA strands during the cDNA biosynthesis

d.

The expression of genes is measured via the signals from cDNAs hybridizing with the specific oligonucleotide probes on the microarray

Discuss
Answer: (a).The two-color microarray uses multiple dyes at times
Q64.
In the analysis of microarray data–If replicated datasets are available, rigorous statistical tests such as t-test and analysis of variance (ANOVA) can be performed to test the null hypothesis that a given data point is not significantly different from the mean of the data distribution.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q65.
Which of the following is incorrect about Classification of microarray data?

a.

For microarray data, clustering analysis identifies coexpressed and coregulated genes

b.

For microarray data, clustering analysis identifies coexpressed but not coregulated genes

c.

For microarray data, clustering analysis identifies and coregulated but not coexpressed genes

d.

Genes within a category have more similarity in expression than genes from different categories.

Discuss
Answer: (a).For microarray data, clustering analysis identifies coexpressed and coregulated genes
Q66.
A supervised analysis refers to classification of data into a set of predefined categories. For example, depending on the purpose of the experiment, the data can be classified into predefined ‘diseased’ or ‘normal’ categories.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q67.
Which of the following is incorrect about Hierarchical Clustering?

a.

The tree-branching pattern illustrates a higher degree of relationship between related gene groups

b.

It is not similar to the distance phylogenetic tree-building method

c.

It produces a treelike structure that represents a hierarchy or relative relatedness of data groups

d.

In the tree leaves, similar gene expression profiles are placed more closely together than dissimilar gene expression profiles

Discuss
Answer: (b).It is not similar to the distance phylogenetic tree-building method
Q68.
Which of the following is incorrect about k-Means Clustering?

a.

k-means clustering produces a dendrogram

b.

It classifies data through a single step partition

c.

It is a divisive approach

d.

In this method, data are partitioned into k-clusters, which are prespecified at the outset

Discuss
Answer: (a).k-means clustering produces a dendrogram
Q69.
Which of the following is incorrect about Self-Organizing Maps?

a.

Clustering by SOMs is in principle similar to the k-means method

b.

It doesn’t involve neural networks

c.

The data points are initially assigned to the nodes at random

d.

It starts by defining a number of nodes

Discuss
Answer: (b).It doesn’t involve neural networks
Q70.
TIGR TM4 is a suite of multiplatform programs for analyzing microarray data.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
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