Genomics and Proteomics MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Genomics and Proteomics, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Genomics and Proteomics MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of Genomics and Proteomics mcq questions that explore various aspects of Genomics and Proteomics problems. Each MCQ is crafted to challenge your understanding of Genomics and Proteomics principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our Genomics and Proteomics MCQs are your pathway to success in mastering this essential Bioinformatics topic.

Note: Each of the following question comes with multiple answer choices. Select the most appropriate option and test your understanding of Genomics and Proteomics. You can click on an option to test your knowledge before viewing the solution for a MCQ. Happy learning!

So, are you ready to put your Genomics and Proteomics knowledge to the test? Let's get started with our carefully curated MCQs!

Genomics and Proteomics MCQs | Page 2 of 12

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Q11.
The _____ resolution genome map is the genomic DNA sequence that can be considered as a type of ______ map describing a genome at the single base-pair level.

a.

highest, physical

b.

lowest, physical

c.

highest, cytological

d.

lowest, cytological

Discuss
Answer: (a).highest, physical
Q12.
Which of the following is untrue about DNA sequencing?

a.

It is now routinely carried out using the Sanger method

b.

This doesn’t make use of DNA polymerases

c.

This involves the synthesis of DNA chains of varying length

d.

The DNA synthesis is stopped by adding dideoxynucleotides

Discuss
Answer: (b).This doesn’t make use of DNA polymerases
Q13.
In DNA sequencing, the fluorescent traces of the DNA sequences are read by a computer program that assigns bases for each peak in a chromatogram.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q14.
The shotgun approach _______ sequences clones from _____ of cloned DNA.

a.

randomly, one end

b.

randomly, both ends

c.

specifically, both ends

d.

specifically, one end

Discuss
Answer: (b).randomly, both ends
Q15.
The shotgun approach does not require knowledge of physical mapping of the clone fragments, but rather a robust computer assembly program to join the pieces of random fragments into a single, whole-genome sequence.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q16.
Despite the multiple coverage, sometimes certain genomic regions remain unsequenced, mainly owing to cloning difficulties.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q17.
The hierarchical genome sequencing approach is ______

a.

entirely dissimilar to the shotgun approach

b.

dissimilar to the shotgun approach

c.

similar to the shotgun approach, but on a larger scale

d.

similar to the shotgun approach, but on a smaller scale

Discuss
Answer: (d).similar to the shotgun approach, but on a smaller scale
Q18.
In hierarchical genome sequencing approach, based on the results of _______ mapping _______of the BAC clones on a chromosome can be determined.

a.

physical, the locations and orders

b.

physical, only the locations

c.

cytological, only the locations

d.

physical, only the orders

Discuss
Answer: (a).physical, the locations and orders
Q19.
The hierarchical approach is ____ and _____ than the shotgun approach because it involves an initial clone-based physical mapping step.

a.

slower, less costly

b.

faster, more costly

c.

faster, less costly

d.

slower, more costly

Discuss
Answer: (d).slower, more costly
Q20.
The whole genome shotgun approach can produce a draft sequence very rapidly because it is based on the direct sequencing approach.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
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