Genomics and Proteomics MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Genomics and Proteomics, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Genomics and Proteomics MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of Genomics and Proteomics mcq questions that explore various aspects of Genomics and Proteomics problems. Each MCQ is crafted to challenge your understanding of Genomics and Proteomics principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our Genomics and Proteomics MCQs are your pathway to success in mastering this essential Bioinformatics topic.

Note: Each of the following question comes with multiple answer choices. Select the most appropriate option and test your understanding of Genomics and Proteomics. You can click on an option to test your knowledge before viewing the solution for a MCQ. Happy learning!

So, are you ready to put your Genomics and Proteomics knowledge to the test? Let's get started with our carefully curated MCQs!

Genomics and Proteomics MCQs | Page 6 of 12

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Q51.
Which of the following is untrue regarding expressed sequence tags (ESTs)?

a.

One of the high throughput approaches to genome-wide profiling of gene expression is sequencing ESTs

b.

They are short sequences obtained from cDNA clones

c.

They serve as short identifiers of full-length genes

d.

They are typically in the range of 800 to 900 nucleotides in length

Discuss
Answer: (d).They are typically in the range of 800 to 900 nucleotides in length
Q52.
To generate EST data, clones in the cDNA library are randomly selected for sequencing from either end of the inserts.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q53.
Which of the following is untrue regarding the drawbacks of expressed sequence tags (ESTs)?

a.

They are often of lowquality because they are automatically generated without verification

b.

Many bases are ambiguously determined, represented by N’s

c.

Frame shift errors and artifactual stop codons are some common errors

d.

Despite of all the failures, the translation the sequences is smooth

Discuss
Answer: (d).Despite of all the failures, the translation the sequences is smooth
Q54.
It has been estimated that up to 11% of cDNA clones may be chimeric.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q55.
Which of the following is untrue regarding expressed sequence tags (ESTs)?

a.

EST libraries can be easily generated from various cell lines, tissues, organs, and at various developmental stages

b.

Although individual ESTs are prone to error, an entire collection of ESTs contains valuable information

c.

Identification of cDNA clone is difficult

d.

ESTs can also facilitate the unique identification of a gene from a cDNA library

Discuss
Answer: (c).Identification of cDNA clone is difficult
Q56.
GenBank has a special EST database, dbEST that contains EST collections for a large number of organisms.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q57.
Which of the following is untrue regarding EST Index Construction?

a.

The goal of the EST databases is to organize and consolidate the largely redundant EST data

b.

The process includes a preprocessing step that removes masks repeats

c.

There is no screening of vector contaminants

d.

The goal of the EST databases is to improve the quality of the sequence information so the data can be used to extract full-length cDNAs

Discuss
Answer: (c).There is no screening of vector contaminants
Q58.
Which of the following is untrue regarding UniGene?

a.

It is an NCBI EST cluster database

b.

Overlapping EST sequences are computationally processed to represent a single expressed gene

c.

Each cluster is a set of overlapping EST sequences

d.

The overlapping EST sequences are computationally processed to represent a set of expressed genes

Discuss
Answer: (d).The overlapping EST sequences are computationally processed to represent a set of expressed genes
Q59.
Which of the following is untrue regarding TIGR Gene Indices?

a.

It is an EST database that the similar type of clustering method from UniGene

b.

It is an EST database that uses a different clustering method from UniGene

c.

It compiles data from dbEST, GenBank mRNA and genomic DNA data, and TIGR’s own sequence databased Sequences are only clustered if they are more than 95% identical for over a fortynucleotide region in pairwise comparisons

d.

None of the mentioned

Discuss
Answer: (a).It is an EST database that the similar type of clustering method from UniGene
Q60.
Which of the following is untrue regarding SAGE?

a.

It stands for Serial analysis of gene expression

b.

It is another high throughput, sequence-based approach for global gene expression profile analysis

c.

It stands for Squared analysis of gene expression

d.

Unlike EST sampling, SAGE is more quantitative in determining mRNA expression in a cell

Discuss
Answer: (c).It stands for Squared analysis of gene expression
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