Structural Bioinformatics MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Structural Bioinformatics, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Structural Bioinformatics MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of Structural Bioinformatics mcq questions that explore various aspects of Structural Bioinformatics problems. Each MCQ is crafted to challenge your understanding of Structural Bioinformatics principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our Structural Bioinformatics MCQs are your pathway to success in mastering this essential Bioinformatics topic.

Note: Each of the following question comes with multiple answer choices. Select the most appropriate option and test your understanding of Structural Bioinformatics. You can click on an option to test your knowledge before viewing the solution for a MCQ. Happy learning!

So, are you ready to put your Structural Bioinformatics knowledge to the test? Let's get started with our carefully curated MCQs!

Structural Bioinformatics MCQs | Page 5 of 10

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Q41.
Members within the ____ fold ______ have evolutionary relationships.

a.

same, always

b.

same, do not always

c.

one, always

d.

different, do not

Discuss
Answer: (b).same, do not always
Q42.
In CATH, Structural domain separation is carried by ___________

a.

manual comparison only

b.

computer programs only

c.

human expertise only

d.

a combined effort of a human expert and computer programs

Discuss
Answer: (d).a combined effort of a human expert and computer programs
Q43.
Which of the following is untrue about SCOP and CATH?

a.

The definition for class in CATH is quite dissimilar to that in SCOP

b.

The definition for class in CATH is based on secondary structure content

c.

Architecture is a unique level in CATH, intermediate between fold and class

d.

The definition for class in CATH is similar to that in SCOP

Discuss
Answer: (d).The definition for class in CATH is similar to that in SCOP
Q44.
SCOP is _______ based on manual comparison of structures by human experts with no quantitative criteria to group proteins.

a.

entirely

b.

almost entirely

c.

not

d.

partially

Discuss
Answer: (b).almost entirely
Q45.
CATH is a combination of manual curation and automated procedure, which makes the process less subjective.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q46.
The formation of _____ is determined by ______ interactions, whereas the formation of ____ is strongly influenced by ______ interactions.

a.

α-helices, long-range, α-helices, short-range

b.

α-helices, long-range, β-strands, short-range

c.

α-helices, short-range, β-strands, long-range

d.

β-strands, short-range, β-strands, long-range

Discuss
Answer: (c).α-helices, short-range, β-strands, long-range
Q47.
The secondary structure prediction methods can be either ab initio based, which make use of single sequence information only, or homology based, which makes use of multiple sequence alignment information.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q48.
Which of the following is untrue regarding Ab Initio–Based Methods?

a.

This type of method predicts the secondary structure based on a single query sequence

b.

This type of method predicts the secondary structure based on a multiple query sequence

c.

It measures the relative propensity of each amino acid belonging to a certain secondary structure element

d.

The propensity scores are derived from known crystal structures

Discuss
Answer: (b).This type of method predicts the secondary structure based on a multiple query sequence
Q49.
The Chou–Fasman algorithm determines the propensity or intrinsic tendency of each residue to be in the helix, strand, and β-turn conformation using observed frequencies found in protein crystal structures.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q50.
The GOR method is based on the “propensity” of each residue to be in one of the two conformational states, helix (H), strand(E).

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (b).False
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