Structural Bioinformatics MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Structural Bioinformatics, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Structural Bioinformatics MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of Structural Bioinformatics mcq questions that explore various aspects of Structural Bioinformatics problems. Each MCQ is crafted to challenge your understanding of Structural Bioinformatics principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our Structural Bioinformatics MCQs are your pathway to success in mastering this essential Bioinformatics topic.

Note: Each of the following question comes with multiple answer choices. Select the most appropriate option and test your understanding of Structural Bioinformatics. You can click on an option to test your knowledge before viewing the solution for a MCQ. Happy learning!

So, are you ready to put your Structural Bioinformatics knowledge to the test? Let's get started with our carefully curated MCQs!

Structural Bioinformatics MCQs | Page 4 of 10

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Q31.
The intramolecular approach does not depend on sequence similarity between the proteins to be compared.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q32.
Which of the following is incorrect about the intramolecular approach?

a.

The method works by generating a distance matrix between residues of the same protein

b.

It generates a string between residues of the same protein

c.

In comparing two protein structures, the distance matrices from the two structures are moved relative to each other to achieve maximum overlaps

d.

By overlaying two distance matrices, similar intramolecular distance patterns representing similar structure folding regions can be identified

Discuss
Answer: (b).It generates a string between residues of the same protein
Q33.
Which of the following is incorrect about Multiple Structure Alignment?

a.

The alignment strategy is different than the Clustal sequence alignment using a progressive approach

b.

All structures are first compared in a pairwise fashion

c.

A distance matrix is developed based on structure similarity scores such as RMSD

d.

The aligned structures create a median structure that allows other structures to be progressively added for comparison based on the hierarchy described in the guide tree

Discuss
Answer: (a).The alignment strategy is different than the Clustal sequence alignment using a progressive approach
Q34.
Which of the following is incorrect about SSAP?

a.

It is a web server that uses an intramolecular distance–based method

b.

Matrices are built based on the Cβ distances of all residue pairs

c.

Dynamic programming approach is not used here

d.

Dynamic programming approach is used

Discuss
Answer: (c).Dynamic programming approach is not used here
Q35.
VAST is a web server that performs alignment using intramolecular approaches only.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (b).False
Q36.
The classification results from both systems, SCOP and CATH are quite dissimilar.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (b).False
Q37.
The first step in structure classification is to remove redundancy from databases.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q38.
The second step in structure classification is to separate structurally distinct domains within a structure.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q39.
The last step in structure classification involves grouping proteins/domains of similar structures.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q40.
Which of the following is untrue about SCOP?

a.

It is a database for comparing and classifying protein structures

b.

It is constructed almost entirely based on manual examination of protein structures

c.

The proteins are grouped into hierarchies of classes, folds, superfamilies, and families

d.

The SCOP families consist of proteins having low sequence identity (>30%)

Discuss
Answer: (d).The SCOP families consist of proteins having low sequence identity (>30%)
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