Structural Bioinformatics MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Structural Bioinformatics, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Structural Bioinformatics MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of Structural Bioinformatics mcq questions that explore various aspects of Structural Bioinformatics problems. Each MCQ is crafted to challenge your understanding of Structural Bioinformatics principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our Structural Bioinformatics MCQs are your pathway to success in mastering this essential Bioinformatics topic.

Note: Each of the following question comes with multiple answer choices. Select the most appropriate option and test your understanding of Structural Bioinformatics. You can click on an option to test your knowledge before viewing the solution for a MCQ. Happy learning!

So, are you ready to put your Structural Bioinformatics knowledge to the test? Let's get started with our carefully curated MCQs!

Structural Bioinformatics MCQs | Page 7 of 10

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Q61.
The early algorithms based their prediction on hydrophobicity scales.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q62.
Predictions solely based on hydrophobicity profiles have lowest error rates.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (b).False
Q63.
The presence of ______ signal peptides can significantly compromise the prediction _______ because the programs tend to confuse hydrophobic signal peptides with membrane helices.

a.

hydrophobic, accuracy

b.

hydrophobic, error

c.

hydrophilic, accuracy

d.

hydrophilic, error

Discuss
Answer: (a).hydrophobic, accuracy
Q64.
Which of the following is untrue regarding TMHMM?

a.

It is a web-based program based on an HMM algorithm

b.

It is trained to recognize transmembrane helical patterns

c.

It is not trained to recognize transmembrane helical patterns

d.

When a query sequence is scanned, the probability of having an Ξ±-helical domain is given

Discuss
Answer: (c).It is not trained to recognize transmembrane helical patterns
Q65.
Which of the following is untrue regarding Phobius?

a.

It is a web-based program designed to overcome false positives caused by the presence of signal peptides

b.

The program incorporates distinct HMM models for signal peptides only

c.

The program incorporates distinct HMM models for signal peptides as well as transmembrane helices

d.

After distinguishing the putative signal peptides from the rest of the query sequence, prediction is made on the remainder of the sequence

Discuss
Answer: (b).The program incorporates distinct HMM models for signal peptides only
Q66.
Which of the following is true regarding Prediction of Ξ²-Barrel Membrane Proteins?

a.

For membrane proteins with Ξ²-strands only, the Ξ²-strands forming the transmembrane segment are amphipathic in nature

b.

For membrane proteins with Ξ²-strands only, the Ξ²-strands forming the transmembrane segment are only hydrophilic in nature

c.

For membrane proteins with Ξ²-strands only, the Ξ²-strands forming the transmembrane segment are only hydrophobic in nature

d.

They contain six to nine residues

Discuss
Answer: (a).For membrane proteins with Ξ²-strands only, the Ξ²-strands forming the transmembrane segment are amphipathic in nature
Q67.
Scanning a sequence by hydrophobicity does not reveal transmembrane Ξ²-strands.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q68.
Coiled coils are super helical structures involving two to more interacting Ξ±-helices from the same or different proteins.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q69.
Which of the following is true regarding Coiled coil?

a.

They have an integral repeat of twenty residues

b.

They have an integral repeat of seven residues

c.

They have an integral repeat of thirty residues

d.

The sequence periodicity doesn’t contribute in designing algorithms to predict the structural domain.

Discuss
Answer: (b).They have an integral repeat of seven residues
Q70.
Which of the following is untrue regarding Coils?

a.

It is a web-based program that detects coiled coil regions in proteins

b.

It scans a window of fourteen, twenty-one, or twenty-eight residues

c.

It scans a window of fourteen or twenty-one residues only

d.

It compares the sequence to a probability matrix compiled from known parallel two-stranded coiled coils

Discuss
Answer: (c).It scans a window of fourteen or twenty-one residues only
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