Modifications and Mutagenesis MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Modifications and Mutagenesis, a fundamental topic in the field of Genetic Engineering. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Modifications and Mutagenesis MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of Modifications and Mutagenesis mcq questions that explore various aspects of Modifications and Mutagenesis problems. Each MCQ is crafted to challenge your understanding of Modifications and Mutagenesis principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Genetic Engineering tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our Modifications and Mutagenesis MCQs are your pathway to success in mastering this essential Genetic Engineering topic.

Note: Each of the following question comes with multiple answer choices. Select the most appropriate option and test your understanding of Modifications and Mutagenesis. You can click on an option to test your knowledge before viewing the solution for a MCQ. Happy learning!

So, are you ready to put your Modifications and Mutagenesis knowledge to the test? Let's get started with our carefully curated MCQs!

Modifications and Mutagenesis MCQs | Page 5 of 8

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Q41.
The minor change in amino acid sequence can lead to _______ effect on three dimensional structure and there _____ in the primary sequence.

a.

huge, may be no change

b.

no, may be huge change

c.

very less, is very less change

d.

huge, would be huge change

Discuss
Answer: (a).huge, may be no change
Q42.
It is often useful to inactivate endogenous genes in an organism. It might be helpful in finding out _________ role of the wild type gene.

a.

biological

b.

chemical

c.

physiological

d.

anatomical

Discuss
Answer: (c).physiological
Q43.
The inactivation of endogenous genes may also be helpful in directing the expression of the mutated gene in the absence of background expression of wild type gene.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q44.
How can mutant strains be produced?

a.

In systematic mutagenesis programmes

b.

In individual organisms

c.

Both by individual organisms and systematic mutagenesis programmes

d.

Apart from these two, other methods are also used

Discuss
Answer: (c).Both by individual organisms and systematic mutagenesis programmes
Q45.
The principle of gene disruption is ________ to replace the endogenous chromosomal copy of a gene with __________

a.

homologous recombination, inactivated gene

b.

reciprocal translocation, inactivated gene

c.

homologous recombination, activated gene

d.

reciprocal translocation, activated gene

Discuss
Answer: (a).homologous recombination, inactivated gene
Q46.
The gene to be disrupted is cloned and a selectable marker is inserted. What should be the effect of selectable marker?

a.

It should have no effect on target gene

b.

It should make the target gene non-functional

c.

There is no restriction; it can be either functional or non-functional

d.

It should improvise the chances of survival of the target gene

Discuss
Answer: (b).It should make the target gene non-functional
Q47.
The disrupted gene is excised from the vector and is inserted into the target organism. The excised gene should be in which form?

a.

Circular

b.

Supercoiled

c.

Either supercoiled or circular

d.

Linear

Discuss
Answer: (d).Linear
Q48.
Stable acquisition of the marker can take place only if a double crossover over the flanking sequence and their chromosomal counterparts causes the marker’s integration into the chromosome.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q49.
If ______ gene is there, the double crossover may leave ________ in the chromosome.

a.

linear, functional copy

b.

circular, functional copy

c.

linear, a non-functional copy

d.

circular, a non-functional copy

Discuss
Answer: (b).circular, functional copy
Q50.
If the target organism contains more than one copy of the gene, what is the effect on these copies?

a.

Only copy is disrupted

b.

All the copies are disrupted

c.

It is difficult to ensure that all the copies are disrupted

d.

Only a specified number of copies are disrupted

Discuss
Answer: (c).It is difficult to ensure that all the copies are disrupted
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